Buy Xifaxanta

What is it used for?

Xifaxanta tablets contain the active ingredient rifaximin, which is a type of medicine called a rifamycin antibiotic. This prescription drug is used to treat infections in the intestine.

This antibiotic acts locally in the intestine and is not absorbed into the bloodstream. It remains 99% within the gut and has few systemic side-effects and few interactions or contraindications. It works by targeting and inactivating a bacterial enzyme called RNA-polymerase. The bacteria use RNA-polymerase to make essential proteins and to copy their own genetic information (DNA). Without this enzyme the bacteria cannot reproduce and they die.

Travellers' Diarrhoea is a stomach and intestinal infection that occurs as a result of unsanitary handling of food. Traveller’s diarrhoea is caused by consuming food or water that has been contaminated by bacteria, viruses or parasites. For further information on prevention and treatment etc please visit NHS Fit for Travel

Irritable Bowel Syndrome (IBS) / SIBO - Clinical trials and published medical papers have shown that rifaximin is effective in treating IBS. Please click here to see the medical details and recommended dosage.
Although this medication is licensed for the treatment of IBS by the FDA, it is not licensed in the UK.

Small intestinal bacterial overgrowth (SIBO)

Small intestinal bacterial overgrowth is a disorder of excessive bacterial growth in the small intestine. Unlike the colon (or large bowel), which is rich with bacteria, the small bowel usually has fewer than 104 organisms per millilitre. Patients with bacterial overgrowth typically develop symptoms including nausea, bloating, vomiting, diarrhoea, malnutrition, weight loss and malabsorption.

How to use?

Travellers' Diarrhoea - Xifaxanta tablets can be taken with or without food. They should be swallowed with a glass of water. The usual dose of Xifaxanta tablets is one tablet to be taken every eight hours for three days (a total of nine doses). You should complete this course even if your symptoms improve.

Irritable Bowel Syndrome (IBS) / SIBO - Clinical trials and published medical papers have shown that rifaximin is effective in treating IBS. Please click here to see the medical details and recommended dosage.

This medication is not for IBS /SIBO with constipation. Please click here to see the relevant medication for IBS / SIBO with constipation.

Please note: Abdominal pain, nausea, vomiting, flatulence, diarrhoea, dyspnoea, headache, depression, dizziness, muscle spasm, rash, pruritus can be common Side Effects of this drug.

Not to be used in:

• People with an allergy to any rifamycin antibiotics such as rifampicin or rifabutin.
• People with diarrhoea containing blood, or who also have a fever.
• People who have experienced eight or more unformed or liquid stools in the previous 24 hours.
• Children and adolescents under 18 years old.

This medicine should not be used if you are allergic to any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Where can I buy online?

You can buy Xifaxanta online with or without a prescription at Medical Specialists pharmacy, after completing a simple online consultation. Just complete an online consultation by clicking the orange button above.

Ask Our Prescriber / Pharmacist

Medical Specialists® are proud of our in-house team of Prescribers, Pharmacists and Experts who carry out the online consultations, dispense medication or help our patients in other ways.

If you would like to ask one of our experts any questions regarding your medication or any other matter, then please feel free to submit your query to us and will get back to you.

For full patient information, please read or print out the leaflet provided at the bottom of this page about Xifaxanta tablets.

Medicines and their possible Side Effects can affect individual people in different ways. The following are some of the Side Effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect. The Side Effects listed above may not include all of the Side Effects reported by the medicine's manufacturer.

Common (affect between 1 in 10 and 1 in 100 people)

• Disturbances of the gut such as abdominal pain, constipation, diarrhoea, wind, bloating and distension, nausea and vomiting.
• Spinning sensation (vertigo).
• Headache.
• Dizziness.
• Feeling of involuntary and painful or ineffective straining
• Fever.

Uncommon (affect between 1 in 100 and 1 in 1000 people)

• Inflammation or infection of the nose and throat.
• Cold sores.
• Thrush infections.
• Cough.
• Runny or blocked nose.
• Dry lips or throat.
• Sinus headache or migraine.
• Shortness of breath.
• Sleepiness.
• Loss of appetite.
• Dehydration.
• Depressed mood or nervousness.
• Difficulty sleeping or abnormal dreams.
• Sensation of pins and needles or numbness.
• Double vision.
• Ear pain.
• Spinning sensation (vertigo).
• Awareness of your heart beat (palpitations).
• Hot flushes.
• Increased blood pressure.
• Changes in the stools such as blood or mucus in stools (see a doctor if you experience this) or hard stools.
• Changes in taste.
• Skin reactions such as rash, blotchy skin or sunburn.
• Muscle pain, cramps or weakness.
• Increased need to pass urine or blood in the urine.
• More frequent periods.
• Feeling weak.
• Flu-like symptoms, sweating or chills.

For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.

Xifaxanta tablets should be taken at least two hours after taking activated charcoal tablets which are sometimes used to treat diarrhoea and wind.

Other medicines containing the same active ingredient

There are currently no other medicines available in the UK that contain rifaximin as the active ingredient.

• Xifaxanta tablets should only be taken for a maximum of three days. If your symptoms do not improve after three days, or come back shortly after you have finished the course, you should see a doctor. Another course should not be taken.
• Antibiotics can sometimes cause inflammation of the bowel (colitis). For this reason, if your diarrhoea gets worse or starts to contain blood or mucus, either during or after taking this medicine, you should consult a doctor immediately.

Not to be used in

• People with an allergy to any rifamycin antibiotics such as rifampicin or rifabutin.
• People with diarrhoea containing blood, or who also have a fever.
• People who have experienced eight or more unformed or liquid stools in the previous 24 hours.
• Children and adolescents under 18 years old.

This medicine should not be used if you are allergic to any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

• The safety of this medicine in pregnancy has not been established. The manufacturer states that it is not recommended for women who are pregnant, or for fertile women who are not using an effective method of contraception. Seek further medical advice from your doctor.
• It is not known if this medicine passes into breast milk, although this is unlikely because the medicine is only minimally absorbed into the bloodstream. The manufacturer recommends that mothers who are breastfeeding should either not take this medicine, or if they wish to take this medicine should stop breastfeeding temporarily during treatment (express and discard milk). Ask your doctor for further advice.

Warnings