Xifaxanta (Rifaximin) - IBS/SIBO without Constipation

Prices from as little as £2.21 a tablet

(Including Private Prescription)

Xifaxanta has been prescribed for many years as en effective treatment for travellers' diarrhoea. However, you can also buy Xifaxanta online for Irritable Bowel Syndrome (IBS) or Small Intestinal Bacterial Overgrowth (SIBO) where constipation is NOT a symptom. Xifaxanta for IBS or SIBO is an unlicensed use, but suitable patients can buy Xifaxanta for IBS or SIBO from our UK online pharmacy by completing a simple online consultation.

As low as £105.95
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  • Can treat IBS/SIBO without constipation (unlicensed use)
  • Active ingredient is Rifaximin
  • Often considered an extremely safe medication
  • Genuine UK medication

What is Xifaxanta for?

Please note: Only buy Rifaximin online if you DO NOT suffer constipation with your IBS or SIBO.

Please note:  When requested in the consultation, please upload evidence of your SIBO diagnosis (such as a breath test, consultant letter, etc.)

Please note: Although Xifaxanta (Rifaximin 200mg) is an effective non-systemic antibiotic primarily used to treat traveller’s diarrhoea, it may be prescribed off-license by Medical Specialists® to treat IBS or SIBO.

Please note: Although this medication is licensed for the treatment of IBS by The Food and Drug Administration (FDA), it is not licensed in the United Kingdom. Although it should be clear what this means, If you are still unsure, please feel free to contact us for more information.

IBS / SIBO - Clinical trials and published medical papers[1] have shown that Rifaximin is effective in treating these conditions. Please click here to see the medical details and recommended dosage.

Irritable Bowel Syndrome (IBS)

A common disorder of the large intestine, believed to be suffered by between 1 and 2 in 10 people in the UK. The condition typically causes pain in your stomach, bloating, and a change in your bowel habits, somethings alternating between bouts of diarrhoea or constipation. There's no cure but you can buy Xifaxanta without a prescription for IBS to help ease the symptoms.

Small Intestinal Bacterial Overgrowth (SIBO)

This is a disorder of excessive bacterial growth in the small intestine. Unlike the colon (or large bowel), which is rich with bacteria, the small bowel usually has fewer than 104 organisms per millilitre. Patients with bacterial overgrowth typically develop symptoms including nausea, bloating, vomiting, diarrhoea, malnutrition, weight loss and malabsorption.

How does Xifaxanta work for IBS and SIBO?

In the body, the active ingredient of Xifaxanta (Rifaximin)is not absorbed into the bloodstream, which minimises potential side effects whilst increasing its ability to act directly on the bacteria that exist within the small intestine.

Many health experts believe that those with IBS/SIBO may have changes in their intestinal microorganisms, and that by targeting these gut microorganisms to treat the condition, symptoms could dramatically improve.

Even better is that unlike other antibiotics, Xifaxanta has minimal impact to the large intestine, thereby reducing the risk of giving you gastrointestinal symptoms or yeast infections.

How to take Xifaxanta for IBS and SIBO

Buy Xifaxanta online for IBS or SIBO - Clinical trials and published medical papers[1] have shown that Rifaximin is effective for treatment. Please click here to see the medical details and recommended dosage.

Do not buy Rifaximin (Xifaxanta) for IBS or SIBO with constipation. Please click here to see the relevant medication for these conditions with constipation.

How long should I take Xifaxanta for IBS and SIBO

Please read the guidance highlighted above. Clinical studies suggest a 7 or 10 day course of Rifaximin at 1,200mg daily can help to improve symptoms. If you are unsure which is best for you, always speak to your own GP or Gastroenterologist.

Xifaxanta (Rifaximin) is supplied in packs of 9 x 200mg tablets. 

Studies have shown the following can help for IBS/SIBO without constiptation:

For a 7 day course: TWO 200mg tablets THREE times a day for 7 days


For a 10 day course: TWO 200mg tablets THREE times a day for 10 days

What are the possible side effects of Xifaxanta?

Side effects are rare, and most people don’t get any. Possible side effects may vary from one person to the next with any medication. You should always read the manufacturer’s Patient Information Leaflet (PIL) before taking this or any other medication.

This will give you important instructions on how and when to take the medication, as well as any possible side effects of the drug.

As this medication is supplied off-label (unlicensed) for IBS / SIBO, together with the medication, we will provide a Medical Specialists® leaflet with guidance for its off-label use. Therefore, you will not receive this leaflet if you buy Rifaximin tablets for travellers’ diarrhoea.

How we package your order

Your medication is placed inside a plain delivery box* for protection, then sealed inside a special tamper-proof Royal Mail envelope before being dispatched from our in-house pharmacy.

  • Discreet plain packaging / No mention of medication
  • Our minimum sized delivery box* to protect the medication in transit is: W - 18cm, H - 6.5cm, D - 8.5cm
  • Royal Mail Tracked 24 or 48 hr (UK addresses)
  • Royal Mail Special Delivery Before 1pm (UK addresses)
  • Royal Mail Local Collect (UK addresses)
  • Royal Mail International Signed For (Overseas addresses)
  • Some delivery types will require you to sign for the parcel
  • Some delivery types will require you to show Photo ID for the parcel
  • Find out more information about delivery types here


1. Saadi M, McCallum RW. (2013) "Rifaximin in irritable bowel syndrome: rationale, evidence and clinical use." PMID 23556126


Purchasing Information

Is Xifaxanta good for IBS?

Ix Xifaxanta good for SIBO?

Why does Xifaxanta (Rifaximin) cost so much?

Can I buy Rifaximin over the counter?

What is the difference between Xifaxan and Xifaxanta?

How It Works
Three easy steps
1. Select treatment

Relax and at your own convenience, hassle-free, choose your medication on any device from anywhere.

2. Complete online consultation

Confidentiality assured as our prescribers check your form, and a safe and secure checkout is guaranteed.

3. Next day discrete delivery

Our pharmacists dispense your treatment conveniently to your home or work so you never have to miss a delivery.

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