Please note that since 2017, Nitrofurantoin has been the most widely prescribed first line treatment for cystitis, although some women may find either Nitrofurantoin or Trimethoprim responds better to their symptoms.
What is Trimethoprim for?
Trimethoprim is an antibiotic used to treat urinary tract infections (UTIs), such as uncomplicated cystitis. Patients must carry on taking this medicine until the course is completed, even if you feel better after the first day for example. Although Nitrofurantoin is more commonly prescribed and is considered a more effective treatment, Trimethoprim is still very effective for some women and their preferred treatment.
How does Trimethoprim work?
Trimethoprim works to stop bacteria from producing a substance called folate. Without folate, the bacteria cannot produce DNA, thus cannot grow and increase in numbers. Trimethoprim therefore stops the infection from spreading. Any bacteria left are killed by the immune system or will eventually die.
How to take Trimethoprim
• Adults: 200mg tablets twice daily for 3 days to treat uncomplicated cystitis.
Choosing Nitrofurantoin or Trimethoprim for Cystitis
Nitrofurantoin is now the most widely prescribed first line treatment for cystitis, although some women may find either Nitrofurantoin or Trimethoprim responds better to their symptoms.
Both are effective antibiotic treatments for cystitis, although there is believed to be increasing antibiotic resistance to Trimethoprim. Up to approximately 30% of bacteria responsible for water infections are resistant to Trimethoprim.
However, some women may find one of the other treatment is more suitable for them and their infection responds better to a particular antibiotic, or they may find they experience less side effects with either Nitrofurantoin or Trimethoprim.
If you are not sure which antibiotic treatment is more suitable for you, your Doctor should be able to offer appropriate guidance.
Ask Our Prescriber / Pharmacist
Medical Specialists® are proud of our in-house team of Prescribers, Pharmacists and Experts who carry out the online consultations, dispense medication or help our patients in other ways.
If you would like to ask one of our experts any questions regarding your medication or any other matter, then please feel free to submit your query to us and will get back to you.
How We Package Your Order
Your medication is sealed in a plain shipping box for protection then placed inside a tamper-proof Royal Mail special delivery envelope before being dispatched from our in-house NHS pharmacy.
For full patient information, please read or print out the leaflet provided at the bottom of this page.
This patient information leaflet is provided for information purposes only. This leaflet information should not be used in contradiction with your Doctor or Pharmacist's advice. Medical Specialists recommend that you carefully read the information leaflet provided with your medication. Medical Specialists will not accept liability for information displayed. Please refer to the leaflet provided with your medication for the latest manufacturer's information.
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