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Medical Specialists® UK Pharmacy
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Buy Constella

buy constella


(Linaclotide 290mcg)

Prices from as little as £39.95*

(*based on private prescription)

Next......Easy 4 step process to obtain this medication in consultation with our in-house prescribers.

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Product Details
Side Effects

What is it?

Constella capsules are a prescription medication that contains the active ingredient Linaclotide which helps to restore normal bowel movement. Constella capsules are used for the treatment of moderate to severe irritable bowel syndrome / SIBO with constipation. This medication is only if you suffer constipation with your IBS / SIBO.

How does it work?

The symptoms of irritable bowel syndrome vary from person to person. Constella is only used for IBS with constipation / SIBO that is causing symptoms such as abdominal pain and bloating. Linaclotide is not absorbed into the bloodstream and works locally in the gut. This is where it binds to receptors called guanylate cyclase C receptors that are found on the walls of the intestine. This reduces abdominal pain and increases the amount of fluid in the gut, which helps loosen the stools and speed up their movement through the bowel.

How do I take?

  • The usual dose is one Constella capsule taken once a day with a drink of water.
  • The capsule should be taken on an empty stomach, at least 30 minutes before a meal. Taking the capsule with food is more likely to cause loose and more frequent stools. (Please see warning below)
  • If you forget to take a dose don’t worry, just leave out the forgotten dose and take your next dose as usual. Do not take a double dose to make up for a missed dose.
  • If you have taken this medicine once a day for four weeks and it does not seem to be helping your symptoms, it is important that you let your doctor know.


  • Female Patients Over 50 years of age - If you have suffered Irritable Bowel Syndrome symptoms within the last 12 months, you will need to see your GP for appropriate tests for ovarian cancer and measurement of your serum CA125 level before we can prescribe this medication. These results MUST be given in one of the additional information boxes provided when you complete your online consultation.
  • This medicine can cause diarrhoea. You should tell your doctor if you experience severe diarrhoea or diarrhoea lasting longer than a week. If you get diarrhoea make sure you drink plenty of fluids or use rehydration sachets to prevent dehydration. Follow the instructions given by your doctor.
  • Bottles of Constella capsules contain a dessicant (silica gel) that stops the capsules absorbing moisture. It is important to keep your Constella capsules in this bottle and keep it tightly closed to protect the capsules from moisture. Do not swallow the silica gel and do not remove it from the bottle. If there are any capsules left in the container 18 weeks after it was first opened these should be disposed of, preferably by returning to your pharmacy.


1. Constella Summary of Product Characteristics, November 2012.
2. Quigley EM et al. Aliment Pharmacol Ther 2013; 37: 49–61.

Where can I buy Constella online?

You can buy Constella with or without a prescription at Medical Specialists, after completing a simple online consultation. Just complete an online consultation by clicking the orange button above. We are the UK’s leading online supplier of prescription medication in the UK and our pharmacy is regulated by the Royal Pharmaceutical Society of Great Britain.

Phamarmacy Team

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Medical Specialists® are proud of our in-house team of Prescribers, Pharmacists and Experts who carry out the online consultations, dispense medication or help our patients in other ways.

If you would like to ask one of our experts any questions regarding your medication or any other matter, then please feel free to submit your query to us and will get back to you.

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How We Package Your Order

Your medication is sealed in a plain shipping box for protection then placed inside a tamper-proof Royal Mail special delivery envelope before being dispatched from our in-house Pharmacy.

  • Discreet Plain Packaging
  • Royal Mail Special Delivery
  • No Mention of Medication

For full patient information, please read or print out the leaflet provided at the bottom of this page.


This patient information leaflet is provided for information purposes only. This leaflet information should not be used in contradiction with your Doctor or Pharmacist's advice. Medical Specialists recommend that you carefully read the information leaflet provided with your medication.  Medical Specialists will not accept liability for information displayed. Please refer to the leaflet provided with your medication for the latest manufacturer's information.
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